Heparinase III Applications
| Heparinase III | Research Grade | Part No. |
| Synonyms | Heparin Lyase III, Heparan sulfate lyase/eliminase, Heparitinase I | 50-012 (0.5 IU/vial) 50-012-001 (0.1 IU/vial) 50-012-002 (Bulk) |
| Source | Flavobacterium heparinum (Recombinant) | |
| EC Number | 4.2.2.8 | |
| CAS Number | 37290-86-1 | |
| Purity | ≥ 95 % by reverse-phase HPLC analysis |
- Production of low- and ultra-low molecular weight heparins (LMWH and ULMWH)
- Characterization of heparin, heparan sulfate (HS), LMWH
- Compositional analysis of glycocalyx in tissues and on cells
- Depolymerization of heparin, HS and chemically modified heparins and molecular weight profiling of heparins and HS
- Production and isolation of oligosaccharides with novel sequences of GlcNH3+ residues
- Quality control testing of heparin and heparin-derived products,
- Quantification of contaminants in heparin such as over-sulfated chondroitin sulfate and persulfonated heparin
- Quantification of process-related impurities
- Glycobiology research,
- Determination of the spacing between S-domains in the HS using the enzymatically digested fragment analysis of HS
- Identification of the biological properties of HS that depend on the integrity of the S-domains
- In vitro host-pathogen interactions in viral infections, in vitro virus-adhesion inhibition studies, cell culture experiments
- In vitro virus plaque inhibition assays
- In vivo inhibition studies of neovascularization and proliferation of capillary endothelial cells
- Mass spectral analysis of heparins and heparan sulfates
- Cancer biology research
- In vitro histochemistry, immunohistochemistry, immunocytochemistry and flow cytometry
